Models of Tumor Dynamics to Improve the Development and Use of Oncology Therapeutics
By Manish Sharma, M.D.
Assistant Professor, Department of Medicine, Section of Hematology/Oncology, University of Chicago


Oncology drug development has traditionally relied on categorical metrics of tumor response and disease progression. Longitudinal data on tumor size and other biomarkers of disease burden can be used to develop models of disease progression with model-based estimates of drug effect. These models can be used to discover more powerful endpoints for clinical trials and predictive markers of response to therapy.  The potential of these models will be discussed using examples in renal cell carcinoma, colorectal cancer, and castrate-resistant prostate cancer.

- Meet and greet with refreshments: 5:30-6:30 pm
- Presentation 6:30-7:30 pm
- Discussion 7:30 – 8:00 pm

Costs: The registration fee covers refreshments. 
$5 for ISoP members and $10 for non-members 
Payment will be in cash at the event.  We cannot accept credit cards.

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To complete your registration, please send an email to [email protected] Please register by Monday, May 16th, end of business, so that we can get an accurate headcount.  If you have registered but find that you cannot attend, please email us at [email protected] to let us know.